ALLAN METZGER, MD: We have the sense that overt caffeine ingestion, too much caffeine, multiple cups of something a day does not do well with bone formation. A little bit of caffeine is probably okay.
NIKI MOHAN: What about race? Now white women and Asian women?
ALLAN METZGER, MD: Yes. White women andAsian women have the greatest problem with osteoporosis. We have a sense that this is not lifestyle but it's genetics -- certain genetic markers that have not been defined yet. Certain parts of the gene, even though we've mapped most of the human genome, we haven't localized the defect -- why Caucasians have a greater risk than black women or intermediate risk like American Indians?
NIKI MOHAN: What kind of tests do you use to detect osteoporosis?
ALLAN METZGER, MD: The most important test is a thing called a DEXA or a QCT, a specific measurement of the mass or density of bone, a bone density test. And most physicians, hospitals, and X-ray units use what's called a DEXA (D-E-X-A). This specifically measures the boney architecture mass and exactly how much calcium is in a very solid or strong bone. An X-ray is a little inefficient.
If you see osteoporosis on an X-ray as an incidental finding, say in a yearly chest X-ray, in a 60-year-old woman, this may be related to the loss of at least 40% of calcium in the bone. You need that much loss to detect it on an X-ray.
NIKI MOHAN: How long does this take and does it hurt?
ALLAN METZGER, MD: The DEXA is probably the best test you can have and recommend. The patient doesn't get undressed. There's no embarrassment. There's no stigma to getting the test. It's painless. It takes five minutes on some of the newer machines. The nice advantage is you can measure different body parts. You can measure the spine and the hips which are the most important areas for fracture and it gives you a risk-relationship to how low the density is and kind of points us in the direction of what we need to do to help the patient.
NIKI MOHAN: Thank you very much Dr. Metzger.